Title |
Hyperdisease in the late Pleistocene: validation of an early 20th century hypothesis
|
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Published in |
The Science of Nature, September 2006
|
DOI | 10.1007/s00114-006-0144-8 |
Pubmed ID | |
Authors |
Bruce M. Rothschild, Richard Laub |
Abstract |
The hypothesis of disease-related large mammal extinction has new support. A unique pathologic zone of resorption was first noticed in a Hiscock Mammut americanum metacarpal. The pathognomonic zone of resorption was present in fifty-nine (52%) of 113 skeletons with feet available for examination. Metacarpals and metatarsals were most commonly affected. Associated rib periosteal reaction is highly suggestive of tuberculosis and the foot lesions were identical to that documented in Bison as pathognomonic for tuberculosis. Recognizing that only a portion of animals infected by infectious tuberculosis develop bone involvement, the high frequency of the pathology in M. americanum suggests that tuberculosis was not simply endemic, but actually pandemic, a hyperdisease. Pandemic tuberculosis was one of several probable factors contributing to mastodon extinction. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Canada | 2 | 3% |
Czechia | 1 | 1% |
Chile | 1 | 1% |
Mexico | 1 | 1% |
United States | 1 | 1% |
Unknown | 74 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 15 | 19% |
Researcher | 15 | 19% |
Student > Bachelor | 12 | 15% |
Student > Master | 9 | 11% |
Other | 6 | 8% |
Other | 15 | 19% |
Unknown | 8 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Earth and Planetary Sciences | 25 | 31% |
Agricultural and Biological Sciences | 22 | 28% |
Social Sciences | 5 | 6% |
Arts and Humanities | 4 | 5% |
Medicine and Dentistry | 3 | 4% |
Other | 12 | 15% |
Unknown | 9 | 11% |