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Therapeutic use of stem cells for cardiovascular disease

Overview of attention for article published in Clinical and Translational Medicine, August 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#32 of 243)
  • High Attention Score compared to outputs of the same age (84th percentile)

Mentioned by

blogs
1 blog
twitter
5 tweeters

Citations

dimensions_citation
48 Dimensions

Readers on

mendeley
103 Mendeley
Title
Therapeutic use of stem cells for cardiovascular disease
Published in
Clinical and Translational Medicine, August 2016
DOI 10.1186/s40169-016-0116-3
Pubmed ID
Authors

Whitney Faiella, Rony Atoui

Abstract

Stem cell treatments are a desirable therapeutic option to regenerate myocardium and improve cardiac function after myocardial infarction. Several different types of cells have been explored, each with their own benefits and limitations. Induced pluripotent stem cells possess an embryonic-like state and therefore have a high proliferative capacity, but they also pose a risk of teratoma formation. Mesenchymal stem cells have been investigated from both bone marrow and adipose tissue. Their immunomodulatory characteristics may permit the use of allogeneic cells as universal donor cells in the future. Lastly, studies have consistently shown that cardiac stem cells are better able to express markers of cardiogenesis compared to other cell types, as well improve cardiac function. The ideal source of stem cells depends on multiple factors such as the ease of extraction/isolation, effectiveness of engraftment, ability to differentiate into cardiac lineages and effect on cardiac function. Although multiple studies highlight the benefits and limitations of each cell type and reinforce the successful potential use of these cells to regenerate damaged myocardium, more studies are needed to directly compare cells from various sources. It is interesting to note that research using stem cell therapies is also expanding to treat other cardiovascular diseases including non-ischemic cardiomyopathies.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 103 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 103 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 23 22%
Student > Master 20 19%
Student > Ph. D. Student 16 16%
Researcher 11 11%
Student > Doctoral Student 4 4%
Other 8 8%
Unknown 21 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 23 22%
Agricultural and Biological Sciences 15 15%
Medicine and Dentistry 14 14%
Engineering 8 8%
Pharmacology, Toxicology and Pharmaceutical Science 5 5%
Other 12 12%
Unknown 26 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 September 2016.
All research outputs
#1,739,914
of 15,414,285 outputs
Outputs from Clinical and Translational Medicine
#32
of 243 outputs
Outputs of similar age
#40,108
of 265,871 outputs
Outputs of similar age from Clinical and Translational Medicine
#1
of 2 outputs
Altmetric has tracked 15,414,285 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 243 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.9. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 265,871 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them