| Title |
Size-dependent antimicrobial properties of sugar-encapsulated gold nanoparticles synthesized by a green method
|
|---|---|
| Published in |
Discover Nano, November 2012
|
| DOI | 10.1186/1556-276x-7-623 |
| Pubmed ID | |
| Authors |
Vivek D Badwaik, Lakshmisri M Vangala, Dillon S Pender, Chad B Willis, Zoraida P Aguilar, Matthew S Gonzalez, Rammohan Paripelly, Rajalingam Dakshinamurthy |
| Abstract |
The antimicrobial properties of dextrose-encapsulated gold nanoparticles (dGNPs) with average diameters of 25, 60, and 120 nm (± 5) and synthesized by green chemistry principles were investigated against both Gram-negative and Gram-positive bacteria. Studies were performed involving the effect of dGNPs on the growth, morphology, and ultrastructural properties of bacteria. dGNPs were found to have significant dose-dependent antibacterial activity which was also proportional to their size. Experiments revealed the dGNPs to be bacteriostatic as well as bactericidal. The dGNPs exhibited their bactericidal action by disrupting the bacterial cell membrane which leads to the leakage of cytoplasmic content. The overall outcome of this study suggests that green-synthesized dGNPs hold promise as a potent antibacterial agent against a wide range of disease-causing bacteria by preventing and controlling possible infections or diseases. |
Mendeley readers
The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 2 | 2% |
| Poland | 1 | 1% |
| Slovenia | 1 | 1% |
| Unknown | 82 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 19 | 22% |
| Researcher | 16 | 19% |
| Student > Master | 14 | 16% |
| Student > Bachelor | 8 | 9% |
| Student > Doctoral Student | 7 | 8% |
| Other | 7 | 8% |
| Unknown | 15 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 18 | 21% |
| Chemistry | 16 | 19% |
| Biochemistry, Genetics and Molecular Biology | 8 | 9% |
| Immunology and Microbiology | 5 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 6% |
| Other | 13 | 15% |
| Unknown | 21 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 November 2012.
All research outputs
#22,756,649
of 25,371,288 outputs
Outputs from Discover Nano
#798
of 1,146 outputs
Outputs of similar age
#172,707
of 193,280 outputs
Outputs of similar age from Discover Nano
#14
of 89 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,146 research outputs from this source. They receive a mean Attention Score of 3.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 193,280 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 89 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.