| Title |
Therapeutic potential of mesenchymal stem cell based therapy for osteoarthritis
|
|---|---|
| Published in |
Clinical and Translational Medicine, August 2016
|
| DOI | 10.1186/s40169-016-0112-7 |
| Pubmed ID | |
| Authors |
John Burke, Monte Hunter, Ravindra Kolhe, Carlos Isales, Mark Hamrick, Sadanand Fulzele |
| Abstract |
Osteoarthritis (OA) is a chronic degenerative disease affecting articular cartilage in joints, and it is a leading cause of disability in the United States. Current pharmacological treatment strategies are ineffective to prevent the OA progression; however, cellular therapies have the potential to regenerate the lost cartilage, combat cartilage degeneration, provide pain relief, and improve patient mobility. One of the most promising sources of cellular regenerative medicine is from mesenchymal stem cells (MSCs). MSCs can be isolated from adipose tissue, bone marrow, synovial tissue, and other sources. The aim of this review is to compile recent advancement in cellular based therapy more specifically in relation to MSCs in the treatment of osteoarthritis. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 40% |
| United Kingdom | 1 | 20% |
| Unknown | 2 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 3 | 60% |
| Members of the public | 2 | 40% |
Mendeley readers
The data shown below were compiled from readership statistics for 143 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | <1% |
| Unknown | 142 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 26 | 18% |
| Student > Master | 25 | 17% |
| Student > Ph. D. Student | 19 | 13% |
| Student > Bachelor | 14 | 10% |
| Student > Doctoral Student | 11 | 8% |
| Other | 23 | 16% |
| Unknown | 25 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 30 | 21% |
| Biochemistry, Genetics and Molecular Biology | 27 | 19% |
| Agricultural and Biological Sciences | 16 | 11% |
| Engineering | 10 | 7% |
| Nursing and Health Professions | 5 | 3% |
| Other | 23 | 16% |
| Unknown | 32 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 October 2016.
All research outputs
#8,534,976
of 25,374,647 outputs
Outputs from Clinical and Translational Medicine
#337
of 1,060 outputs
Outputs of similar age
#134,195
of 371,400 outputs
Outputs of similar age from Clinical and Translational Medicine
#7
of 15 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,060 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.2. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 371,400 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.