| Title |
Regulation of centriolar satellite integrity and its physiology
|
|---|---|
| Published in |
Cellular and Molecular Life Sciences, August 2016
|
| DOI | 10.1007/s00018-016-2315-x |
| Pubmed ID | |
| Authors |
Akiko Hori, Takashi Toda |
| Abstract |
Centriolar satellites comprise cytoplasmic granules that are located around the centrosome. Their molecular identification was first reported more than a quarter of a century ago. These particles are not static in the cell but instead constantly move around the centrosome. Over the last decade, significant advances in their molecular compositions and biological functions have been achieved due to comprehensive proteomics and genomics, super-resolution microscopy analyses and elegant genetic manipulations. Centriolar satellites play pivotal roles in centrosome assembly and primary cilium formation through the delivery of centriolar/centrosomal components from the cytoplasm to the centrosome. Their importance is further underscored by the fact that mutations in genes encoding satellite components and regulators lead to various human disorders such as ciliopathies. Moreover, the most recent findings highlight dynamic structural remodelling in response to internal and external cues and unexpected positive feedback control that is exerted from the centrosome for centriolar satellite integrity. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 148 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 148 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 38 | 26% |
| Researcher | 18 | 12% |
| Student > Master | 18 | 12% |
| Student > Bachelor | 15 | 10% |
| Student > Doctoral Student | 9 | 6% |
| Other | 17 | 11% |
| Unknown | 33 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 59 | 40% |
| Agricultural and Biological Sciences | 35 | 24% |
| Medicine and Dentistry | 8 | 5% |
| Neuroscience | 4 | 3% |
| Engineering | 2 | 1% |
| Other | 7 | 5% |
| Unknown | 33 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 August 2016.
All research outputs
#15,492,086
of 23,794,258 outputs
Outputs from Cellular and Molecular Life Sciences
#2,969
of 4,151 outputs
Outputs of similar age
#232,569
of 370,846 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#31
of 52 outputs
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So far Altmetric has tracked 4,151 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
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