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Fampridine and quality of life in individuals with multiple sclerosis

Overview of attention for article published in SpringerPlus, July 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

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1 blog
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2 X users

Citations

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11 Dimensions

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35 Mendeley
Title
Fampridine and quality of life in individuals with multiple sclerosis
Published in
SpringerPlus, July 2016
DOI 10.1186/s40064-016-2776-2
Pubmed ID
Authors

Yoshimasa Sagawa, Eloi Magnin, Laura Paillot, Thierry Moulin, Pierre Decavel

Abstract

Fampridine improves walking in patients with multiple sclerosis (pwMS). However, little is known about its impact on the quality of life (QoL) of pwMS. This study aimed to evaluate the contribution of fampridine on the QoL of pwMS and to determine if improvements in QoL are best associated with walk respondents. Fifty pwMS were included in this study. The PERSEPP scale and the GaitRite system were used to evaluate QoL and gait respectively. QoL was evaluated 7 days before fampridine (Pre1), on the day the fampridine treatment was initiated (Pre2), and 14 and 21 days after fampridine (Post1 and Post2 respectively). Gait was assessed at Pre-1, Pre-2 and Post-1. For all patients, fampridine had significant effects (p = 0.05-10(-4), d = 0.25-0.45) on the Overall, Relationship difficulties, Fatigue, Time perspective and Symptoms QoL indices and for gait parameters (p = 0.05-10(-4), d = 0.17-0.38). Non-respondents scored significant effects (p < 0.05-0.01, d = 0.32-0.41) for Overall, Time perspective and Symptoms QoL indices, whereas respondents scored significant effects (p < 0.05-0.01, d = 0.51-0.8) for Overall, Relationship difficulties, Fatigue and Symptoms. The QoL of pwMS improved after fampridine, suggesting a real benefit in their lives. However, the contributions to the overall QoL index seem different between groups.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 3%
Unknown 34 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 23%
Student > Master 4 11%
Researcher 4 11%
Student > Ph. D. Student 4 11%
Other 2 6%
Other 3 9%
Unknown 10 29%
Readers by discipline Count As %
Nursing and Health Professions 5 14%
Medicine and Dentistry 5 14%
Neuroscience 4 11%
Psychology 3 9%
Agricultural and Biological Sciences 2 6%
Other 3 9%
Unknown 13 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 August 2016.
All research outputs
#4,034,884
of 22,881,154 outputs
Outputs from SpringerPlus
#242
of 1,851 outputs
Outputs of similar age
#72,034
of 354,667 outputs
Outputs of similar age from SpringerPlus
#35
of 230 outputs
Altmetric has tracked 22,881,154 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,851 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 354,667 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 230 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.